Patient's question:
Asexuality. Menstruated at 12, always normal. During high school, occasionally experienced mild pain, delay, or early occurrence, but all within the normal range.Doctor's answer:
Increase exercise to reduce weight, correct endocrine and metabolic disorders exacerbated by obesity, reduce insulin resistance and hyperinsulinemia, lower IGF-1, increase IGfBP-1, and simultaneously increase SHBG to reduce free androgen levels. Weight loss can restore ovulation in some obese women with PCOS and prevent the occurrence of type 2 diabetes and cardiovascular diseases. Metformin treatment can be used in both diabetics and non-diabetics, effectively reducing weight, improving insulin sensitivity, lowering insulin levels, reducing hair growth, and even restoring menstruation (25%) and ovulation. Since obesity and insulin resistance are the main causes of PCOS, any drug that can reduce weight and increase insulin sensitivity can treat this syndrome.