Patient's question:
Hello, I would like to ask what are the causes of prolonged semen liquefaction time? My cousin has been married for several years, but has not had children yet. The family is very anxious and urging him to go to the hospital for check-ups. The results showed that there was a problem with his semen, specifically that the sperm did not liquefy. Could you please tell me what are the causes of sperm liquefaction?Doctor's answer:
Ejaculate liquefaction failure is commonly caused by conditions such as seminal vesiculitis and prostatitis, which lead to insufficient secretion of fibrinolysin by the prostate; deficiencies in trace elements (such as magnesium, zinc, etc.); congenital absence of the prostate; and other factors. It is generally believed that the secretions of the prostate and seminal vesicles participate in the coagulation and liquefaction processes of semen. The coagulation factor produced by the seminal vesicles causes semen to coagulate, while the liquefaction factors produced by the prostate, such as proteolytic enzymes and fibrinolysin, cause semen to liquefy. Once inflammation occurs in the seminal vesicles or prostate, it can disrupt the secretion of these factors, leading to an increase in coagulation factors or a decrease in liquefaction factors, resulting in semen liquefaction failure.