What are the reasons for high prolactin?

Patient's question:

Doctor, I have experienced a significant decrease in menstrual flow and galactorrhea recently, but I am not pregnant. After examination, the doctor said it is due to high prolactin levels. I don't know what the reason for this is.

Doctor's answer:

① Pituitary or sellar region tumors;
② Hypothyroidism;
③ Drug-induced, including dopamine receptor antagonists and estrogens, etc.;
④ Chronic renal failure;
⑤ Prolactin (PRL) is the largest stress hormone in the human body, and any physical stress state can cause a rapid increase in PRL.

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