Patient's question:
Hello doctor, I would like to ask what causes of sperm liquefaction failure there are. I have a condition of semen liquefaction failure, and I don't know how I got it. We really want to have a child, but we can't get pregnant, could it be related to this reason? How should I be treated? What are the factors that cause sperm liquefaction failure?Doctor's answer:
1. Mycoplasma, Chlamydia trachomatis, and Neisseria gonorrhoeae infection: If a patient is infected with mycoplasma, it can lead to dysfunction of the accessory glands, causing changes in the composition of semen directly, resulting in semen not liquefying and thus affecting fertility.2. Prostate diseases: Prostate diseases can cause a patient to experience semen not liquefying. Experts explain that the liquefaction and coagulation of semen are regulated by coagulating proteins and liquefying factors in the semen. As enzymes that act as liquefying factors, when prostate secretion activity decreases, their activity weakens continuously, leading to the condition of semen not liquefying in patients.
3. Idiopathic non-liquefaction: Some patients with non-liquefiable semen may also suffer from idiopathic non-liquefaction, which has very poor outcomes in clinical treatment.