Chemical pharmaceutical process

Author: Jin Xueping, Editor-in-Chief
Publisher:
Publish Date: 2006-01-01
Features: This book is a professional textbook for the Chemical Pharmaceutical major in national secondary vocational schools of medicine and pharmacy. It is uniformly organized and written by the National Research Association of Medical Vocational and Technical Education. The book is divided into three parts: General Theory, Specific Topics, and Experiments. The General Theory introduces the selection of synthetic process routes for drug synthesis, research on synthetic processes, pilot plant scale-up and production process procedures, safe production, labor protection, and GMP production of raw pharmaceutical materials, as well as techniques for preventing and treating "three wastes" in pharmaceutical factories, and improvements in pharmaceutical processes. The Specific Topics section covers phase-transfer catalytic technology, column chromatography separation technology, and the synthetic process routes, production principles, and production processes of four representative drugs: hydrocortisone, benorilate, loxoprofen sodium, and chloramphenicol. The Experiments section includes the synthesis and purification of paracetamol, lidocaine, benorilate, and vitamin B intermediates. This book can serve as a textbook for relevant majors in chemical engineering and biomedical vocational education, as well as a training manual for employees of chemical pharmaceutical production enterprises.