Patient's question:
In March 2004, I had an abortion surgery, after which I developed cervical erosion. In April 2005, I had an electrocautery treatment, which resolved the erosion. However, my leukorrhea remained yellow and excessive. I used a lot of medication and suppositories, but it hasn’t improved to this day. Last month, I had a leukorrhea culture and drug sensitivity test, which indicated a Candida infection. The test showed sensitivity to several medications, but after taking them, my condition still hasn’t improved. What should I do? Why isn’t it getting better?First follow-up question: After the drug sensitivity test, I took terbinafine, but it still hasn’t shown any improvement.
Doctor's answer:
Hello: Treatment Principles1. Local Treatment: Suitable for some cutaneous and mucocutaneous candidiasis. Clotrimazole cream or propylene glycol solution, 2-3 times daily, for 1-2 weeks. Nystatin ointment or solution, 2-3 times daily, for 1-2 weeks. Clotrimazole or nystatin vaginal tablets, 1 tablet nightly, for 1-2 weeks.
2. Systemic Treatment: Fluconazole is the first choice for oral and esophageal candidiasis. After the initial dose, 100 mg/day for 2-3 weeks; for vaginal candidiasis, 150 mg as a single dose. If recurrent, 150 mg/day for 3 days, with 150 mg taken before each menstrual period for several months; for systemic infections, the initial dose is 400 mg, followed by oral or intravenous administration, with the duration determined by the condition. Dosage should be adjusted based on creatinine clearance in cases of poor renal function. Itraconazole is typically taken at a dose of 100-200 mg/day.