AIDS Testing Methods and Applications

Author: Li Jingyun, Editor-in-Chief
Publisher:
Publish Date: 2006-03-01
Features: Since the approval of the first HIV antibody ELISA test kit by the U.S. FDA in 1985, significant advancements have been made in HIV detection technologies and methods. Currently, there are various methods targeting multiple detection objectives, suitable for diverse specimen types, employing multiple detection models, and meeting various purposes. These methods play a crucial role in the diagnosis of HIV infection, assessing antiviral treatment efficacy, formulating and adjusting antiviral treatment regimens, and ensuring blood safety. This book includes HIV detection technologies used for etiological diagnosis of AIDS, assessing antiviral treatment efficacy, molecular epidemiological surveys, and antiviral immunological research, making it suitable for technical personnel engaged in HIV detection and research. The book introduces HIV and its related detection methods and applications used in AIDS prevention and control. The content covers not only common HIV antibody screening and confirmation tests but also common qualitative and quantitative detection methods targeting HIV itself, including HIV antigens, HIV proviral DNA, HIV viral load, HIV drug resistance, HIV strain isolation and cultivation, and phenotypic identification. It also briefly introduces the detection methods for HIV-related immunological indicators, such as HIV antiviral immunity and CD4+ T lymphocyte detection. The book further discusses the applications of HIV detection technologies in the field of AIDS prevention and control, such as HIV screening for blood donors, special issues in infant HIV detection, and methods for screening and evaluating antiretroviral drugs. It also includes biosecurity and quality management related to HIV detection, such as the risks and prevention of occupational HIV infection and laboratory quality management and control. This book is suitable for health prevention personnel and clinical doctors engaged in AIDS prevention and control, as well as for researchers involved in AIDS research.