What are the causes of pediatric ADHD?

Patient's question:

The boy is 11 years old and has been treating this disease for a long time. He has also been taking medication, but there has been no improvement. I am very frustrated, and many methods have not worked. Please ask: What are the causes of ADHD in children?

Doctor's answer:

The etiology of childhood ADHD remains unclear to date, and it may be related to the following factors:
(1) The mother of the child often has numerous complications during pregnancy or the perinatal period, frequently with a history of heavy smoking or drug use.
(2) Intergenerational genetic factors, such as: the child's blood relatives (e.g., siblings, father) exhibiting more hyperactive or inattentive behaviors. The prevalence rate in monozygotic twins is as high as 51%–64%. There is also a higher incidence of alcoholism, antisocial personality disorders, and hysteria among relatives.
(3) Although the results of neurotransmitter and enzyme tests are often contradictory, they represent a testable approach to understanding the etiology of this condition.
(4) Severe lead poisoning can cause devastating toxic encephalopathy, dementia, and other neurological harm, but it remains unclear how mild lead poisoning could lead to ADHD.

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