Patient's question:
I only got pregnant with my first baby when I was 32 years old. In the early stages, I had a Down syndrome screening which was low-risk. In the middle stage, the doctor suggested that at 30, I should have a non-invasive detailed examination. I want to know if a low-risk result from the early detailed examination still requires a non-invasive detailed examination? The help I need: To avoid the non-invasive detailed examination if the result is low-risk?Doctor's answer:
A Down syndrome screening is a test that involves extracting pregnant women's serum to examine the concentrations of alpha-fetoprotein, human chorionic gonadotropin, and free estriol in maternal serum. It also integrates factors such as the's estimated due date, weight, age, weight, and gestational age at the time of blood collection to estimate the risk coefficient of giving birth to a fetus with congenital defects. There are many interfering factors, and the accuracy rate is only 70%.Non-invasive prenatal testing (NIPT) involves collecting 10ml of pregnant women's peripheral blood, extracting free DNA, and using next-generation high-throughput sequencing technology combined with bioinformatics analysis to predict the risk rate of the fetus suffering from chromosomal aneuploidy diseases (such as trisomy 21, also known as Down syndrome, trisomy 18, and trisomy 13).