Patient's question:
Pregnant for 3 months, the first prenatal check-up involved a detailed examination of folic acid genes, which resulted in CT and AA genotypes. Is it necessary to continue taking folic acid until the baby is born, and is there anything else that needs to be digested?Doctor's answer:
It is recommended to enhance nutrition, prevent harmful contact, and maintain a positive mindset. During the fourth month of pregnancy, it is advisable to visit the hospital to schedule a prenatal screening for Down syndrome. The C677T mutation in the C677 gene can increase enzyme activity by 35% in the CT heterozygous type, while the TT homozygous type can further increase enzyme activity by 70%. The wild-type (CC) has normal folate catabolic function. Compared to the CC type of C677T, the CT type, TT type, and CT+TT type can increase the risk of folate catabolic disorders; compared to the AA type of A1298C, the AC type, CC type, and AC+CC type can also increase the risk of folate catabolic disorders. I hope this information is helpful to you. Wishing you good health!