Patient's question:
I have an itchy lower body, and my underwear is always yellow. What's going on? What could cause a fetus to have a cleft lip?Doctor's answer:
The exact cause and pathogenesis of developmental and fusion disorders have not yet been fully clarified. Research suggests that they may be divided into two aspects: genetic factors and environmental factors, and are also related to factors such as nutrition, genetics, infection, and endocrine.1. Genetic factors. In patients with cleft lip, similar deformities may also be found in their direct or collateral relatives, suggesting that cleft lip deformity is related to genetics to some extent. Genetic studies also consider cleft lip to be a polygenic genetic disease.
2. Environmental factors. During the first three months of pregnancy, when the physiological state of the mother is affected or disrupted, it may impact the development of the embryonic facial and maxillary region. Examples include nutritional deficiencies, infections, drug factors, physical injuries, and alcohol and smoking.