Why does Obstructive Azoospermia Occur

Patient's question:

What are the causes of obstructive azoospermia? After examination, my husband was found to have obstructive azoospermia. Generally speaking, what factors can cause obstructive azoospermia?

Doctor's answer:

The occurrence of obstructive azoospermia is related to the following factors:
1. Inability to produce sperm due to testicular inflammation, often caused by mumps, though other infections can also lead to this condition.
2. Ingestion of cottonseed oil can cause testicular atrophy and damage to germ cells, resulting in the production of dead sperm.
3. Severe varicocele can impair blood circulation in the testes, leading to excessively high local temperature, which is unfavorable for sperm production, thereby causing azoospermia.
4. Sertoli cell syndrome is caused by congenital or acquired factors that lead to the loss of germ cells, leaving only Sertoli cells and resulting in azoospermia.
5. Obstruction in the pathway of sperm passage can cause the emitted semen to be sperm-free, such as when gonorrhea sometimes blocks the vas deferens.

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