Is it serious if HPV16 and HPV18 are positive?

Patient's question:

Is HPV16 and HPV18 positive serious?

Doctor's answer:

CIN is a general term for a group of diseases, including cervical dysplasia and cervical intraepithelial carcinoma. CIN I rarely transforms into cancer; CIN II and CIN III have a small chance of becoming cancerous, and are referred to as precancerous lesions. The progression from cervical precancerous lesions to cervical cancer involves a process of cervical epithelial dysplasia → in situ carcinoma → invasive carcinoma, which typically takes about 10 years, or even 20 years. Based on your medical history, examination, and age, the current examination suggests the possibility of cervical precancerous lesions.
Biopsy: CIN 2-3. The best and most effective treatment plan is transvaginal cervical conization (TCRC).

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