Patient's question:
Menstruation stopped starting in March, obesity for 3 years, needs medication to have a period, no medication means no period. Diagnosis is polycystic ovary syndrome, high androgen levels, low progesterone.Doctor's answer:
Increase exercise to reduce weight, correct endocrine and metabolic disorders exacerbated by obesity, reduce insulin resistance and hyperinsulinemia, lower IGF-1, increase IGfBP-1, and simultaneously increase SHBG to reduce free androgen levels. Weight loss can restore ovulation in some obese women with PCOS and prevent the occurrence of type 2 diabetes and cardiovascular diseases. Metformin treatment can be used for both diabetic and non-diabetic individuals, effectively reducing weight, improving insulin sensitivity, lowering insulin levels, and even reducing hair growth or restoring menstruation (25%) and ovulation. Since obesity and insulin resistance are the main causes of PCOS, any drug that can reduce weight and increase insulin sensitivity can treat this syndrome.