Patient's question:
Breasts have become significantly larger than before, without pain or discomfort. I would like to ask for your advice and see if the problem is serious?? Patient gender: Patient age:Doctor's answer:
The occurrence of the disease is primarily due to an absolute or relative increase in estrogen levels in the body, or an increased sensitivity of breast tissue to it. Both men and women secrete both androgens and estrogens in their bodies, but the difference in proportion reflects gender differences. Therefore, any factors that lead to high estrogen levels or reduced androgen secretion can trigger this condition. For example:1. Diseases of the adrenal cortex, the primary site of estrogen secretion, can cause abnormally elevated estrogen levels.
2. When the liver, the main site of estrogen metabolism, becomes diseased and liver function declines, estrogen accumulates significantly in the body, leading to the condition.
3. The testes are the primary organs for androgen secretion. Disorders such as testicular tumors or congenital testicular hypoplasia can reduce androgen secretion while relatively increasing estrogen levels, thereby causing the condition.
4. Other diseases, such as hypothalamic-pituitary disorders, thyroid diseases, diabetes, sexual differentiation abnormalities, and chronic colitis, can also lead to the condition. Certain medications, such as progesterone, isoniazid, tricyclic antidepressants, and digitalis, can affect estrogen metabolism and induce breast enlargement.