What are the causes of luteal dysfunction?

Patient's question:

Already had two miscarriages, went to the hospital for a check-up, and the doctor said I have luteal phase dysfunction.

Doctor's answer:

1. Luteal phase defect: Refers to premature luteal regression, with a luteal phase duration of ≤10 days. Clinical manifestations include frequent menstruation, shortened cycles, spotting before menstruation, and menorrhagia. It is often associated with infertility and early miscarriage. Endometrial pathology shows irregular maturation or incomplete secretion.
2. Luteal atrophy insufficiency: Also known as luteal phase dysfunction, where the corpus luteum fails to fully regress within 3–5 days, or regression is prolonged, or the endometrium continues to secrete a certain amount of progesterone during the menstrual period, leading to irregular endometrial shedding, extended menstruation, and intermittent bleeding. When combined with premature luteal regression, it manifests as frequent menstruation and menorrhagia. It is more common after induced abortion or miscarriage, and is often associated with uterine fibroids, endometrial polyps, and adenomyosis.

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