Patient's question:
I really want to get pregnant, but I have been tested positive for antisperm antibodies and cervical moderate erosion. Can I still get pregnant? The doctor said I haven't given birth yet, and cervical erosion can be ignored for now. Is that correct? What should I do?Medical history: Two years ago, I had a medication-induced abortion, and I haven't been pregnant since.
Doctor's answer:
Hello: According to your condition, it is best to actively treat the condition before considering pregnancy.Cervical erosion is a common inflammatory condition of the female reproductive tract, classified into three degrees (mild, moderate, and severe) based on the proportion of the cervix affected by erosion. Treatment methods include non-invasive and invasive treatments. Local treatment using medication applied vaginally is a non-invasive approach, but it is not very effective for moderate to severe cervical erosion. Invasive treatments involve local cervical treatment using methods such as phototherapy, cryotherapy, laser, and electrocautery. This method may cause minor damage to the cervix locally and sometimes affect its ability to dilate during childbirth, but it does not cause infertility. In fact, severe cervical erosion or acute infections, if left untreated, can lead to infertility. Therefore, for women who have not borne children and suffer from cervical erosion without affecting pregnancy or acute infections, cervical laser treatment can be performed after childbirth.
Anti-sperm antibodies are one of the most common causes of female infertility. Studies have found that 15.18% of infertile women have anti-sperm antibodies. Under normal circumstances, both sperm and embryos are foreign bodies to the mother. Therefore, each sexual act may be like an immunization, but only a small number of women develop anti-sperm antibodies. The reasons are as follows: (1) Seminal plasma contains some immunosuppressive factors that can inhibit the function of T and B cells. These factors can be wrapped around the surface of sperm, preventing the female immune system from reacting to them. (2) Enzymes in seminal plasma can affect the expression of antigens on the surface of sperm. (3) After sperm enter the vagina, their surface is quickly covered by a layer of maternal protein.