What is the meaning of luteal phase deficiency?

Patient's question:

What is the meaning of luteal phase deficiency? Will it affect pregnancy? Do you need to take any medication?

Doctor's answer:

Hello: Luteal phase defect refers to insufficient progesterone secretion by the corpus luteum or premature luteal regression, leading to poor secretion of the endometrium and consequently difficulty in implantation of the zygote or early pregnancy miscarriage. Luteal phase defect may be related to insufficient secretion of LH and FSH by the pituitary gland or excessive or insufficient secretion of prolactin by the pituitary gland. In some cases, it may be due to the immaturity of the zygote itself, its insensitivity to gonadotropins. In other cases, it may be related to insufficient ability of the corpus luteum to synthesize progesterone or an imbalance in the ratio of estrogen and progesterone. It is recommended that you and your partner come to our hospital for a comprehensive and systematic examination to identify the factors or causes of infertility or subfertility, and receive targeted treatment. Do not miss the best age for pregnancy. Wish you health!

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