Patient's question:
Hello doctor, I would like to consult about what causes semen to remain liquid. My friend got married a year later than me, but now their child is already 2 years old, and we haven't been able to conceive yet. Yesterday, the doctor said it was an issue with my husband's semen not liquefying. Does this significantly affect fertility? What are the causes of semen not liquefying?Doctor's answer:
1. Mycoplasma, Chlamydia trachomatis, and Neisseria gonorrhoeae infection: If a patient is infected with mycoplasma, it can lead to dysfunction of the accessory glands, causing changes in the composition of semen directly, resulting in semen not liquefying and thus affecting fertility.2. Prostate diseases: Prostate diseases can cause semen not to liquefy. Experts explain that the liquefaction and coagulation of semen are regulated by coagulating proteins and liquefying factors in the semen. As enzymes that act as liquefying factors, when prostate secretion activity decreases, their activity weakens continuously, leading to semen not liquefying in patients.
3. Idiopathic non-liquefaction: Some patients with non-liquefying semen also suffer from idiopathic non-liquefaction, which has very poor outcomes in clinical treatment.