Patient's question:
How to treat leukoplakia of the vulva? Can it be cured?Doctor's answer:
Hello: "Leukoplakia of the external genitalia" refers to epidermal thickening caused by lesions, loss of pigment in the basal epidermal layer, and reduced superficial dermal blood vessels, leading to a decrease in color or white appearance of the skin or mucosa of the external genitalia. Women suffering from "leukoplakia of the external genitalia" often fear that it may be a precancerous lesion. In recent years, extensive clinical experiments have confirmed that its canceration rate is only about 2%. In 1975, the International Society for Vulvar Diseases decided to abolish the term "leukoplakia of the external genitalia" and refer to the condition as "white lesions of the external genitalia" or "chronic vulvar dystrophy." Patients with white external genital skin often remain unaware due to the lack of sensation, and the condition is usually discovered by a doctor. Some patients, however, may notice it during a visit to the clinic due to itching in the external genital area. Why does the skin of the external genitalia turn white? The exact cause remains unclear, but it is relatively well understood that when the skin of the external genitalia develops certain diseases, excessive keratinization occurs in the affected epidermis, and a reduction in melanocytes leads to paler skin. The affected skin may thicken like leather, or it may become thin, dry, and prone to cracking, even developing ulcers or hard nodules. If the color of the external genital skin turns white, whether or not itching is present, it is advisable to seek medical examination. Particular attention should be paid if the skin is thickened, rough, elevated, ulcerated, cracked, or has hard nodules, and surgical treatment may be necessary if needed. Since "white lesions of the external genitalia" are relatively stubborn, long-term treatment and regular follow-ups are essential. Follow-up intervals of 3 to 6 months are recommended. With persistent treatment, generally satisfactory results can be achieved. Medication may include vitamin supplements. If itching is severe and affects sleep, mild sedatives can be taken. Locally, 1% hydrocortisone and 1–2% testosterone cream can be applied.