What methods can be used to treat primary amenorrhea?

Patient's question:

Detailed medical condition and consultation purpose: I have primary amenorrhea, can it be cured?

Doctor's answer:

Hello, the treatment principles for amenorrhea are as follows:
1. Oral ethinyl estradiol, 0.25–0.5 mg per dose, once nightly, for 20 days. Repeat after stopping the medication for 8–10 days, for a total of 3 cycles.
2. Intramuscular injection of progesterone, 20 mg per dose, once daily, for 3 days. Withdrawal bleeding may occur 3–7 days after stopping the medication. If the next menstrual period does not arrive on schedule, repeat the injection 1–3 cycles.
3. Oral ethinyl estradiol, 0.25–0.5 mg per dose, once daily, for 20 days. After stopping the medication, inject progesterone 10–20 mg per dose, once daily, for 5 days. Withdrawal bleeding may occur 3–7 days after stopping the medication. This can be used for 3 cycles, but attention should be paid to the dosage and timing of medication to avoid menstrual disorders and affect the efficacy.
4. Alternatively, oral norethisterone can be taken, 5 mg per dose, once monthly. After symptom improvement, the maintenance dose is 1–2 mg per dose, once every 1–2 months. However, caution should be exercised in patients with asthma, impaired heart and kidney function, depression, migraine, diabetes, abnormal liver function, thyroid disorders, uterine fibroids, and other conditions.

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