Patient's question:
I've been divorced from my wife for many years, and we've never been able to have children. My wife has irregular periods, and the amount of blood flow is also not very much. Sometimes when we have a detailed check of the follicles, they are very small or even absent. The doctor said it might be due to premature ovarian failure, and advised us to get checked as soon as possible.Doctor's answer:
1. Signs: Basal body temperature is high. Gynecological examination reveals thin vaginal mucosa, few rugae, congestion, and atrophic uterus.2. Laboratory tests and other examinations: Endocrine hormone tests show significantly elevated FSH and LH levels, and significantly decreased E2 levels, all reaching menopausal levels. It requires three tests to confirm the diagnosis. PRL levels are normal.
3. Vaginal smear: Reflects estrogen levels that are too low, with the presence of basal cells or a predominance of low-layer cells.
4. Laparoscopic examination or laparoscopic ovarian biopsy: In premature ovarian failure, the ovaries appear small, enlarged, and follicles are not visible. No primordial follicles are observed under the microscope, with fibrosis of the ovarian stroma. Anti-ovarian antibodies can be found within the ovaries. In the absence of a reaction, the ovaries are of normal size, with multiple small follicles visible both macroscopically and microscopically. The ovaries