Patient's question:
Female, 36 years old, with one child. Since 2014, she has had abnormal leukorrhea, resembling white, and after a thorough examination at the hospital, it was diagnosed as trichomoniasis. In 2017, during a unit health check, a TCT test revealed moderate cervical inflammation, and an HPV test was positive for high-risk type 16. The prenatal doctor prescribed anti-HPV interferon, and she took a total of 10 boxes over a 20-day course. Two months after stopping the medication, a follow-up TCT test showed severe inflammation, with an HPV detection value of 5413.87. A biopsy revealed chronic cervical inflammation with papillary dysplasia, with areas classified as CN1. The doctor's treatment plan was a LEEP. Additionally, she consulted another doctor, who recommended a temporary rigorous treatment. Currently, she is using Baofukang and interferon alternately every other day. As of today, she has been taking medication for 27 days, and her leukorrhea has returned to normal. She wants to consult the doctor about her condition.Doctor's answer:
In fact, there is currently no evidence to prove that the recurrence of cervical lesions is related to the level of HPV values. For acute HPV infection, it can be imagined that the obtained values will be very high. From the perspective of the disease recurrence mechanism, whether it will become cancerous depends on how the virus integrates into the key of cell DNA, as well as the level of the cells that have been integrated. So, this is actually a pure probability issue, and also an all-or-nothing issue—either it integrates into the key.