Patient's question:
Previously, my menstrual cycle had not arrived for over two months. After a thorough examination, the doctor believed I had polycystic ovary syndrome (PCOS). After taking progesterone for one day, my period arrived on the third day. The doctor questioned insulin resistance. During the menstrual period, my fasting blood glucose was 4.6 mmol/L, and my fasting insulin was 3.51 uIU/mL. My insulin levels one hour after glucose intake were 58.27, and two hours after were 43.07. The blood glucose levels one and two hours after glucose intake were not measured. Is this a relatively severe case of insulin resistance? I feel that my insulin levels after drinking glucose are not particularly high in absolute terms, but they are relatively high compared to my fasting levels. Should I take metformin tablets?Doctor's answer:
The insulin level at 1 hour is 5-20 times that of fasting, and it should basically return to the fasting state 2-3 hours after a meal. Your fasting insulin level is normal, and it did not rise 2 hours after a meal, indicating insulin resistance.2. You need to take oral metformin while also paying attention to your diet—low sugar, low fat, and increased activity.
3. Metformin also has a therapeutic effect on polycystic ovary syndrome (PCOS) and does not interfere with pregnancy. You can stop taking it once pregnancy is confirmed.