Taxol production via culture

Author: Mei Xingguo
Publisher:
Publish Date: 2003-10-01
Features: This book systematically summarizes the research experience and key technologies of the national key research project—Taxus cell culture for the production of paclitaxel. It introduces the induction of Taxus callus, the screening of high-yield cell lines, the optimization of culture media, the biosynthetic pathway and metabolic regulation of paclitaxel, the kinetics and modeling of Taxus cell culture, large-scale Taxus cell culture, the analysis and detection of paclitaxel, and the separation, purification, and structural identification of paclitaxel. This monograph can serve as a reference for colleagues engaged in plant cell culture, drug research, and production, as well as for graduate and undergraduate students in biological engineering.