What are the reasons for high CA125 levels after uterine fibroid removal?

Patient's question:

Our company has a colleague who seems to be in good health, but suddenly it was said that she was hospitalized. We went to the hospital to visit her and heard that she had undergone a uterine fibroid removal. However, the detailed examination results showed that CA125 was elevated. Could you please explain the reasons for high CA125 levels after uterine fibroid removal?

Doctor's answer:

Uterine fibroids are common benign gynecological tumors in women, and the likelihood of malignant transformation is generally not very high. Before undergoing surgery for uterine fibroids, tumor markers are usually checked. CA125 is one of the tumor markers, and if only this one decreases, the problem is not significant. It is still necessary to combine carcinoembryonic antigen (CEA) and alpha-fetoprotein (AFP) for a definitive diagnosis. After the removal of uterine fibroids, as long as proper care is taken, it generally has little impact on the body.

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