Exploration of the Etiology of Metabolic Syndrome and Clinical Practice

Author: Zhu Zhiming
Publisher:
Publish Date: 2005-08-01
Features: This book compiles the latest research findings and provides a comprehensive and systematic introduction to the basic concepts of metabolic syndrome, its epidemiological characteristics, related risk factors, clinical assessment and risk prediction, current research trends, etiology and pathophysiological mechanisms, and the features of insulin resistance. It also covers the central regulation of metabolic syndrome, neurohumoral factors, related genes, and cellular signal transduction, as well as inflammation and oxidative stress, and experimental animal models. The book details the characteristics of target organ damage caused by metabolic syndrome, including myocardial hypertrophy, endothelial dysfunction, intimal and medial vascular lesions, early renal damage, and prethrombotic state. It also discusses the clinical complications of metabolic syndrome, such as hypertension, dyslipidemia, obesity, diabetes, coronary heart disease, nephropathy, cerebrovascular disease, and peripheral vascular disease. Additionally, it explores the features of metabolic syndrome in children and adolescents, gynecological diseases, and liver-related metabolic syndrome, along with gender differences. The book evaluates preventive and therapeutic measures, including multifactorial risk intervention, moderate exercise, dietary control, health education, medication, surgery, and interventional therapy. The content is novel and practical, making it suitable for clinical physicians, researchers, and graduate students working in cardiology, endocrinology and metabolism, and related specialties.