Patient's question:
Where is the best treatment for immunological infertility? Hello, doctor, my friend has been diagnosed with immunological infertility, and she is very worried about her future fertility. Where should she go for treatment? Where is the best treatment for immunological infertility?Doctor's answer:
The hazards of immunological infertility include the following points:1. Blocking sperm from penetrating cervical mucus, anti-sperm antibodies can cause sperm to clump together, hindering sperm motility. Sperm immobilizing antibodies exhibit cytotoxic reactions, leading to sperm death or impairing sperm motility. Additionally, they may also affect sperm metabolism and the function of sperm condensin proteins.
2. Impairing the movement of sperm enzymes, inhibiting the aggregation function of the zona pellucida and the corona radiata, including:
① Acrosin: Enhances sperm penetration through the zona pellucida and promotes fertilization;
② Hyaluronidase: Facilitates the aggregation of the corona radiata. Sperm antibodies primarily inhibit the activity of hyaluronidase, thereby affecting sperm aggregation.