Does folic acid overdose cause miscarriage?

Patient's question:

The doctor told me to take folic acid and eat one pill, but I took three pills a day when I was more than 40 weeks pregnant. The placenta stopped growing and developing. I want to ask, can excessive folic acid cause miscarriage?

Doctor's answer:

A deficiency in folic acid metabolism can lead to embryonic arrest, while an excess of folic acid does not cause embryonic arrest. The normal physiological requirement for folic acid is 0.4 to 0.8 milligrams per day. If you have a high-risk deficiency in folic acid metabolism, you can take 4 to 5 milligrams of folic acid per day. Therefore, the recurrence of embryonic arrest is not related to the amount of folic acid consumed; the key is whether the embryo itself has chromosomal abnormalities or significant changes.

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