Patient's question:
I've been married for several years, and so far, we haven't had any children. I'm very anxious about it and don't know if it's my problem. I've asked my husband to get checked, but he refuses. I'm afraid my condition might worsen. If I'm diagnosed with immune infertility, how should I treat it?Doctor's answer:
Hello, immunological infertility refers to infertility caused by immunological factors. Immunological infertility accounts for approximately 10-30% of infertile patients, including various types such as anti-sperm antibodies, anti-endometrial antibodies, anti-oocyte antibodies, and others. In clinical diagnosis, the most common form is immunological infertility caused by the production of anti-sperm antibodies. Due to inflammation in the female reproductive tract, local secretion increases, allowing autoimmune-related cells to enter the reproductive tract. Simultaneously, changes in the permeability of the reproductive tract mucosa enhance the absorption of sperm antigens. Additionally, bacterial, viral, and other infectious agents may act as natural adjuvants, increasing the body's autoimmune response to sperm antigens. As a result, anti-sperm antibodies reappear in the local reproductive tract and bloodstream, affecting sperm vitality.