Patient's question:
What is the immunosuppressive method for treating immune infertility? I have been married for several years, but so far, we don't have any children. I am very anxious myself and don't know if it's my problem. I asked my husband to get checked, but he refuses. I'm very afraid that my condition will worsen. What is going on?Doctor's answer:
About 10% to 20% of infertility cases are immunological. The treatment methods include:(1) Barrier therapy: Women with sperm alloimmunological infertility who use condoms for 3 to 6 months can prevent further stimulation of sperm antigens by the female. After the antibody titer disappears, decide on the ovulation period to have intercourse manually, with the hope of achieving pregnancy.
(2) Immunosuppressive therapy: Corticosteroid drugs can be used to treat immunological infertility. For example, prednisone 5mg is used three times a day for two weeks before menopause. There are reports of local use of hydrocortisone in the vagina to treat infertile women with anti-sperm antibodies in cervical mucus. Reports indicate that the pregnancy rate ranges between 20% and 45%.