Patient's question:
I've been married for several years now, but we still don't have any children. I'm very anxious about it and don't know if it's my problem. I've asked my husband to get checked, but he refuses. I'm very worried that my condition might worsen. How can I treat immune infertility?Doctor's answer:
Hello, immunological infertility refers to infertility caused by immunological factors. Immunological infertility accounts for 10-30% of infertility cases, among which there are hidden anti-sperm antibodies, anti-endometrial antibodies, anti-ovum antibodies, and other types of immunological infertility. In clinical diagnosis, the most common form is immunological infertility caused by the production of anti-sperm antibodies. Due to reproductive tract inflammation in women, local secretion increases, allowing autoimmune cells to enter the reproductive tract. At the same time, the permeability of the reproductive tract mucosa changes, reducing the maturation of sperm antigens. Moreover, bacterial and viral infection factors may act as natural adjuvants, reducing the body's autoimmune response to sperm antigens. As a result, anti-sperm antibodies reappear in the local reproductive tract and bloodstream, affecting sperm vitality and hindering fertilization, leading to infertility.