Drug synthesis reaction technology and methods

Author: Li Lijuan Ye Changlun
Publisher:
Publish Date: 2005-07-01
Features: This textbook is divided into two parts: theory and practice. The theoretical part consists of 10 chapters, each with post-lesson exercises; the practical part includes 13 experiments. Chapters 2 to 8 cover the basic knowledge of drug synthesis, classified by different types of unit reactions, with the evolution of functional groups in organic compounds as the main thread. Starting from the structural characteristics of reactants, students learn commonly used organic synthesis reactions in drug synthesis. While explaining reaction theory and principles, the focus is placed on practical aspects such as raw materials and reagents, reaction conditions, selectivity control, and application examples. New technologies, methods, and reagents currently used in research and production are also introduced appropriately. Chapters 9 to 10 summarize and integrate comprehensive application-oriented knowledge, including group protection, element organic compounds, and their applications—common techniques and methods used in drug synthesis—to complete the content system and adapt to the development needs of drug synthesis technology. This arrangement ensures strong logicality and systematic structure, making it easier to learn and master. The experimental training part emphasizes the practical application of theoretical knowledge and hands-on operational skills. The examples provided cover the operation techniques and methods of various types of unit reactions, as well as the application of some new technologies. This book is intended for use by vocational and technical colleges specializing in pharmaceutical technology, and can also serve as a reference for adult education, secondary vocational teaching, vocational training, as well as technical personnel engaged in the production, development, and research of drugs, intermediates, and fine chemicals.