Patient's question:
Married for many years, I have been actively trying to conceive with my husband, but there has been no good news so far. I am very anxious. What methods can be used to treat immunological infertility quickly?Doctor's answer:
Immune infertility refers to infertility caused by immune factors. Immune infertility accounts for approximately 10-30% of infertility cases, including various types such as anti-sperm antibodies, anti-endometrial antibodies, anti-ovum antibodies, and other immune-related infertility. Clinically, the most common form is immune infertility caused by the production of anti-sperm antibodies. Due to reproductive tract inflammation in women, local secretion increases, allowing autoimmune-related cells to enter the reproductive tract. Simultaneously, changes in the reproductive tract mucosa enhance the processing of sperm antigens. Additionally, bacterial and viral infection factors may act as natural adjuvants, increasing the body's autoimmune response to sperm antigens. As a result, anti-sperm antibodies reappear in the local reproductive tract and bloodstream, interfering with sperm vitality and hindering fertilization, leading to infertility.