Patient's question:
After getting married to my husband, I have always wanted to have a little baby as soon as possible, but there has been no good news so far. A few days ago, I went for a check-up and found out that I have infertility. I felt like the sky was falling down. Please ask: What are the causes of immunological infertility?Doctor's answer:
Referring to the sperm and seminal plasma of the male as antigens that produce antibodies in the female body, causing sperm agglutination or loss of motility. Under normal circumstances, women do not produce autoimmune reactions, but approximately 15%-18% of infertile women have anti-sperm antibodies, possessing local autoimmune reactions. This refers to some infertile women whose cervical mucosa and endometrium contain lymphoid cells that produce immunoglobulin G and A, and the cervical mucus contains anti-sperm immunoglobulin G, A, and M. Therefore, the cervix and female reproductive tract have a local autoimmune effect against sperm. Immune infertility is an easily occurring gynecological disease.