Patient's question:
I and my wife are doing IVF at the hospital. The doctor said it's not good. Why does the quality of the embryo degrade after thawing, and sometimes there are no embryos for transplantation?Doctor's answer:
During the freezing process, the embryo needs to be cooled from normal physiological temperature to ultra-low temperature, and during the thawing process, it needs to be restored from ultra-low temperature back to physiological temperature. Such significant temperature changes or fluctuations may affect the survival and biological activity of the embryo, and even lead to cell death, which is known as cryodamage. Under the same conditions, the recovery rate of high-quality embryos is higher than that of non-high-quality embryos. The quality of the embryo depends on several factors, such as the conditions of the patient and their partner, the culture system, and the embryo culture environment. However, the most critical factor is the patient's own condition. Only by obtaining high-quality eggs and sperm can high-quality embryos be obtained.