Introduction to Molecular Biology

Author: Zhu Hao
Publisher:
Publish Date: 2003-08-01
Features: The rapid development of molecular biology has generated a vast amount of data, and the relationships among them are becoming increasingly complex. Computational molecular biology is the new science that deals with this data. The rapid development of molecular biology has generated a vast amount of data, and the relationships among them are becoming increasingly complex. Computational molecular biology is the new science that deals with this data. This book primarily introduces representative computational problems in molecular biology and some effective methods for solving these problems. It specifically includes: basic concepts of molecular biology; two important mathematical objects, strings and graphs, and the basic concepts of algorithms; sequence comparison and classical dynamic programming algorithms; DNA fragment assembly techniques; DNA physical mapping problems and an approximate algorithm for physical mapping as well as heuristics; mathematical problems related to phylogenetic tree construction and certain algorithms for constructing specific types of phylogenetic trees; mathematical models for studying sequence differences in DNA and dynamic programming methods for RNA structure prediction as well as protein alignment methods; and finally, it introduces DNA computing.