Patient's question:
What does a 1:154 result on the Down syndrome screening mean? What should the normal value be? I'm very concerned. Date of birth: February 25, 1983 (29 years old), Weight: 64KG, Gestational Week: 19+2, LMP Test Results: Test Item Test Result Test Unit MOM Value AFP 30.68 g/ml 0.4554 HCG 50298.38 mlU/ml 2.1395 uE 31.43 g/ml 0.8118 (I didn't understand the data above) Prenatal Screening Results: Down Syndrome: 1:154 OSB:Doctor's answer:
Analysis of the condition: Down syndrome screening is a method that involves drawing the pregnant woman's blood to detect the concentration of alpha-fetoprotein (AFP) and human chorionic gonadotropin (HCG) in the maternal serum, and then calculating the risk coefficient of giving birth to a child with Down syndrome by combining the pregnant woman's estimated due date, age, weight, and gestational age at the time of blood collection. The optimal time for screening is between the 15th and 20th weeks of pregnancy.Advice: If the Down syndrome screening result is greater than 1/270, it is considered high-risk. However, Down syndrome screening is still a probabilistic screening, and further diagnostic tests such as amniocentesis or umbilical cord blood sampling for chromosome analysis are required to confirm the diagnosis. Therefore, there is no need to panic. It is recommended to undergo amniocentesis and fetal chromosome testing to clarify the diagnosis.