Patient's question:
ABO hemolytic disease often occurs in the second pregnancy but can also partially occur in the first pregnancy. This is because there are substances in nature that are similar to A(B) antigens, which O-type blood mothers are often exposed to before pregnancy. Subsequently, these similar blood type antigen substances can stimulate O-type blood mothers to produce A(B) antibodies.1. What are the substances similar to A(B) antigens in nature?
2. What things in daily life contain substances similar to A(B) antigens?
Doctor's answer:
Analysis of the condition: Hello! The AB blood group substance is widely present in certain plants, parasites, and bacteria in nature. Because the ABO antigen cluster on human red blood cell membranes is a type of structurally simple oligosaccharide, some bacteria on their surfaces have similar sugar chain structures, and thus possess the same antigenicity as human ABH. These bacteria are widely found in natural dust, food, and even the intestines.Suggestions: It may just be a common, ordinary intestinal infection. Under continuous stimulation from these bacteria, the human A or B antigens are adsorbed onto the red blood cells. When the mother is exposed to them again, a rapid allergic reaction may occur.