Patient's question:
Healthy, she has the same blood type as me. I wonder what problems would arise if both husband and wife are type O blood?Doctor's answer:
My husband and I are both Type O blood, and our daughter is doing great! The fact is, if one person is Type O and the other is a different blood type, the baby could potentially develop hemolytic disease. During my prenatal checkup, the doctor asked my husband what his blood type was. When he heard it was O, the doctor didn’t say anything. If it weren’t, then an ABO hemolysis test would have been required. So you should be grateful that both of you are Type O. Clinically, neonatal hemolytic disease is quite common, and the fundamental cause of this disease is incompatibility between the couple’s blood types. The baby inherits half of its genetic material from the father and half from the mother, so the baby could inherit the mother’s blood type or the father’s blood type.If the fetus in the mother’s body has a different blood type from the mother, the mother’s body becomes ‘sensitized,’ triggering the immune system, which then produces antibodies that reject the baby’s blood type. These antibodies bind to the surface of the baby’s red blood cells, leading to hemolysis, and the baby will develop hemolytic disease. According to reports, the causes of neonatal hemolytic disease are mainly divided into two types: ABO blood group incompatibility and Rh blood group incompatibility. In China, the most common type is ABO blood group incompatibility. The mothers of children with ABO hemolytic disease are often Type O, while the babies are usually Type A or Type B.