What are the causes of pediatric IgA nephropathy?

Patient's question:

My colleague Xiao Lin has been on leave these days. Her daughter has been diagnosed with pediatric IgA nephropathy. She also has a severe upper respiratory infection and is experiencing edema. She needs to take care of her daughter at home. I would like to know what the cause of this disease is.

Doctor's answer:

Hello, the etiology is not yet fully clear and is related to multiple factors. Most scholars believe that this condition is caused by the deposition of IgA-containing circulating immune complexes in the kidneys. The antigens in the complexes may be related to viruses, bacteria, or certain components from food that cause infections in the respiratory or gastrointestinal tract mucosa.

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