Few, weak, and poor; balanced translocation of chromosomes

Patient's question:

Sperm density is less than 210^6/ML, A/B sperm are almost non-existent

Doctor's answer:

Hello!
The male has a balanced translocation. Theoretically, the sperm produced would be 1/18 normal, 1/18 balanced, and the rest would be unbalanced sperm. This would increase the risk of early miscarriage in the female and the risk of congenital defects in the fetus. Although the theoretical probability of bad outcomes is relatively high, due to the large number of sperm released during a single ejaculation by the male and the rigorous internal selection process in the female's body, the actual miscarriage rate is not as high.
For your situation, if the male's semen quality is acceptable, the first recommendation is to try pregnancy again after adjusting both partners' conditions and avoiding other factors that may cause early miscarriage or fetal defects. It is recommended to undergo amniocentesis between the 16th and 20th weeks of pregnancy to rule out any adverse fetal conditions.

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