Why is the crossmatching test performed during clinical blood transfusion?

Patient's question:

Why is the crossmatching test performed during clinical blood transfusion?

Doctor's answer:

Because the antibodies and antigens in human blood are very complex. It needs to be checked whether the recipient can accept the donor's blood. Sometimes, even if the ABO blood type is the same, a reaction may occur. If such blood is transfused, it may cause severe transfusion reactions, hemolysis, or even death in the recipient. Additionally, blood typing can also reveal occasional errors in blood type identification. In such cases, the blood is considered incompatible.

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