Cancer immunotherapy

Author: G. Stiller P. Wald
Publisher:
Publish Date: 2004-02-01
Features: Over the past 10 years, cancer immunology research has made significant advancements. New theories and insights have led to the development of many novel cancer treatment strategies, which have been applied in clinical trials. As one of the ultimate hopes for conquering cancer, immunotherapy has become a focal point of research in this field. The original English edition of this book was published by Wiley-VCH and written by internationally renowned experts in the field, aiming to comprehensively and systematically reflect the rapidly evolving research area of cancer immunotherapy. The book consists of 17 chapters, discussing the immune system components that can be developed for treatment at the molecular and cellular levels of tumor genetic mechanisms, and exploring different immunotherapy principles used in clinical trials. The content includes identifying universal tumor-associated T cell epitopes, serum determinants of tumor cells, tumor-associated antigen processing and presentation, T cells in tumor immunity, the regulation and loss of major histocompatibility complex (MHC), immune cells in the tumor microenvironment, immunosuppressive factors in tumor immunity, IL-10 in tumor immunity, the development of tumor vaccines using dendritic cells, hybrid cell vaccines for tumor immunotherapy, the principles and strategies of using heat shock proteins (HSPs) for tumor immunotherapy, the application of CpG motifs in bacterial DNA for cancer immunotherapy, T-cell body therapy, the application of bone marrow transplantation in immunotherapy, the application of immune cytokines in biotherapy for malignant tumors, immunotoxins and recombinant immunotoxins in cancer treatment, etc. This book is intended for researchers in immunology, tumor biology, medicine, and related fields, as well as advanced undergraduate and graduate students in relevant disciplines.