Down syndrome screening

Patient's question:

Risk of Down Syndrome: 1:812
Risk of Trisomy 18: 1:42321
Risk of Open Neural Tube Defect: 1.07
Is this normal? Should I do NIPT?

Doctor's answer:

It involves testing the concentrations of alpha-fetoprotein (AFP), human chorionic gonadotropin (β-hCG), free estriol (uE3), and Inhibin A in a pregnant woman's blood, and then using a computer to precisely calculate the risk of each pregnant woman carrying a fetus with Down syndrome, taking into account the pregnant woman's age.

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