Patient's question:
History of treatment and effectiveness for 3 days of recurrent cough: Cephalexin, Dexamethasone, and Lopinavir were administered via injection for three days, but the effect was unsatisfactory. What kind of assistance is needed: How is Ganoderma lucidum effective?Doctor's answer:
The two free hydroxyl groups in the structure of andrographolide succinate hemiesters connect with the potassium ion (K+) and sodium ion (Na+) of potassium bicarbonate and sodium bicarbonate, respectively. It is stable within a pH range of 6—8, reacts with acids to form a displacement reaction, releases Na~, reduces andrographolide to a hemiesters, and reduces solubility, leading to precipitation. Its aqueous solution is prone to hydrolysis, hence it should be avoided from contact with acids, alkalis, or drugs containing sodium bisulfite or sodium metabisulfite as antioxidants. Penicillin and cephalosporin drugs reach a neutral pH, and when mixed with andrographolide, no significant reaction occurs within a short period. Therefore, they can be used in combination with andrographolide. Theophylline is an alkaline drug.