Patient's question:
The father of the child is a Marfan patient. The child is 18 years old, 85 cm tall, and weighs 13 kg. An echocardiogram revealed mild mitral and tricuspid valve regurgitation, and there is a slight pectus excavatum.Is the child also a Marfan patient? If it cannot be confirmed whether the child is a Marfan patient, what is the probability that the disease can be inherited from the child's father to the child across generations?
Treatment history and effectiveness: No treatment has been administered.
What kind of help do you need: I want to know the probability of Marfan inheritance across generations. Is my child a Marfan patient?
Doctor's answer:
According to your description, Marfan syndrome is a hereditary connective tissue disease that is inherited in an autosomal dominant manner across generations. The characteristics of the disease include long and disproportionate limbs, fingers, and toes, as well as significantly taller stature than average. It is often accompanied by cardiovascular system abnormalities, particularly split heart valve abnormalities and aortic aneurysms. The disease may also affect other organs, including the lungs, eyes, dura mater, and hard palate. It is recommended to take the child to the local hospital for a thorough examination to confirm the diagnosis.