Combinatorial chemistry

Author: Nicholas K. Terrett
Publisher:
Publication Date: 1999-07-01
Features: This book introduces the history and current state of combinatorial chemistry, emphasizing the solid-phase supports, linking molecules, compound library synthesis and screening methods, and structure identification methods of active compounds used in combinatorial chemistry techniques, as well as the encoding techniques used for identifying active molecular structures. The book discusses solid-phase combinatorial library synthesis and liquid-phase combinatorial library synthesis, providing examples of the synthesis methods of various organic molecular libraries such as peptides, oligonucleotides, non-peptide oligomers, and small-molecule heterocyclic compounds. It also introduces the application of analytical techniques such as IR, NMR, and MS in combinatorial chemistry. This book introduces the history and current state of combinatorial chemistry, emphasizing the solid-phase supports, linking molecules, compound library synthesis and screening methods, and structure identification methods of active compounds used in combinatorial chemistry techniques, as well as the encoding techniques used for identifying active molecular structures. The book discusses solid-phase combinatorial library synthesis and liquid-phase combinatorial library synthesis, providing examples of the synthesis methods of various organic molecular libraries such as peptides, oligonucleotides, non-peptide oligomers, and small-molecule heterocyclic compounds. It also introduces the application of analytical techniques such as IR, NMR, and MS in combinatorial chemistry.