What are the causes of macrovesicular steatosis?

Patient's question:

My husband is quite overweight and also loves to drink alcohol. A few days ago, he went out drinking and then vomited severely. We took him to the hospital, and the doctor examined him and said he has large droplet fatty liver. What could be the reason for this?

Doctor's answer:

Hello! The causes of steatotic fatty liver include: pediatric malnutrition, gastrointestinal diseases, pancreatic diseases, obesity, intestinal bypass surgery, and long-term parenteral nutrition, among others; diabetes, galactosemia, glycogen storage disease, fructose intolerance, and others; ethanol intoxication, long-term use of adrenal cortical hormones or hepatotoxic drugs; hepatitis C and hepatitis E, and other systemic viral infectious diseases, among others.

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