Patient's question:
Abortion after 49 days of amenorrhea, other tests are normal, just a balanced translocation of chromosomes 3 and 16Doctor's answer:
Balanced Translocation: Human cells contain 23 pairs (46 chromosomes). The number and structure of chromosomes are relatively constant and cannot be arbitrarily increased or decreased, otherwise it will lead to changes. For example, Down syndrome is caused by having an extra chromosome 21 compared to normal individuals. It may reduce fertility in offspring. Pregnant women with balanced translocation have a high rate of miscarriage, or to say, a low pregnancy rate. The solution to this problem is to undergo third-generation in vitro fertilization, i.e., PGD technology, which can screen the chromosomes of embryos and select healthy embryos for transfer.